publicacions científiques

2024

Aguilar, Kevin; Jakubek, Patrycja; Zorzano, Antonio; Wieckowski, Mariusz, Primary mitochondrial diseases: The intertwined pathophysiology of bioenergetic dysregulation, oxidative stress and neuroinflammation. Eur J Clin Invest, e14217. https://doi.org/10.1111/eci.14217

CheShImP: Democratising Magnetic Resonance Spectroscopic Imaging Data Processing
Under Revision

Codony S., Jora B., Santos-Caballero M., Qiu Q., Calvó-Tusell C., Turcu A.L.; Prischi F., Bartra C., Val C., Morisseau C., Pérez B., Bertrán A., Osuna S., Corpas R., Griñán-Ferré C., Galdeano C., Loza M.I., Pallàs M., Sanfeliu C., Hammock B. D., Brea J., Feixas F., Conte M.R., Cobos E.J., Vázquez S., (2024) Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain.
Enviado y en revisión a Journal of Medicinal Chemistry

Eills, James ; Mitchell, Morgan W. ; Rius, Irene Marco ; Tayler, Michael C. D. Live magnetic observation of parahydrogen hyperpolarization dynamics. arXiv preprint arXiv:2402.10766, 2024
DOI:
https://doi.org/10.48550/arXiv.2402.10766
URL:
https://arxiv.org/abs/2402.10766

Gómez Jordi and Torrent Marc, Benchmarking of docking strategies to dock protein-protein interaction inhibitors.
Publicación en preparación.
Pendiente de envío en junio de 2024

Grau, S; Vela, JM; Gurt, A; Barceló-Vidal, J; Ojeda, F; López, I; Gómez-García, L; Loza, MI; Martín-García, E; Maldonado, R; Monfort, J. Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients. Journal of Infection
Enviado para revisión

Llano R., Brea J.M., Ardao I., Pata M., Martínez A.L., Macía M., Loza M.I. (2024) Exploring Cytokine Profiles in Pregnancy: A Study on Preterm Labor Indicators in Amniotic Fluid and Urine.
Enviado y en revisión a BMC Pregnancy and Childbirth.

Leveraging Magnetic Resonance Imaging to Study Biocompatible Scaffolds Diffusion and Perfusion for Lab-on-a-Chip Systems
Under Submission

Lorca, C.; Fernández-Rhodes, M.; Milán, J.A.S.; Mulet, M.; Elortza, F.; Miguel, A.R.; Callado, L.F.; Meana, J.J.; Mur, M.; Batalla, I.; Vilella. E.; Serra A.; Gallart-Palau X. Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome. Biomedicines 2024, 12, IN PRESS

Lymperidou, Aikaterini; Iraola-Guzmán, Susana; Martinez-Gonzalez, Judith; Bracons Cucó, Guillem; Escribà-Montagut, Xavier; Huertas, Marta; Mateo-Navarro, Ramon; Sarrat-González, David; Frid, Santiago; González Ruiz, Juan Ramon; Labarga, Alberto; De Cid, Rafael (2024). DATOS-CAT: OMOP-Common Data Model framework for the GCAT Cohort
Under Submission

Martinez-Gonzalez J, Sarrat-González D, Mateo-Navarro R et al. DATOS-CAT: Leveraging ELIXIR ecosystem for the standardization, integration and federated analysis of population-based biomedical data [version 1; not peer reviewed]. F1000Research 2024, 13(ELIXIR):549 (poster)
DOI: https://doi.org/10.7490/f1000research.1119723.1
URL: https://f1000research.com/posters/13-549

Martinez-Gonzalez, Judith; Aguiló-Castillo, Sergi; Sarrat-González, David; Lymperidou, Aikaterini; Mateo-Navarro, Ramon; Bracons Cucó, Guillem; Huertas, Marta; González Ruiz, Juan Ramon; De Cid, Rafael; Frid, Santiago; Capella-Gutiérrez, Salvador; Labarga, Alberto (2024). DATOS-CAT: Leveraging OMOP CDM for the standardization, integration and analysis of population-based biomedical data
Under Submission

Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Kalani, Ladan; Jorge-Torres, Olga C.; Esteller, Manel; Ausio, Juan; Abian, Olga; Velazquez-Campoy, Adrian (2023) Extending MeCP2 interactome: Canonical nucleosomal histones interact with MeCP2. Nucleic Acids Research
DOI: 10.1093/nar/gkae051
URL: https://academic.oup.com/nar/article/52/7/3636/7600452

PEREZ-CARRIÓN, M.D.; POSADAS, I.; and CEÑA, V. Nanoparticles and siRNA: A new era in therapeutics?. Pharmacol. Res. 201:107102. 2024
DOI: 10.1016/j.phrs.2024.107102.
URL: https://pubmed.ncbi.nlm.nih.gov/38331236/

Sarrat-González, David; Martinez-Gonzalez, Judith; Escribà-Montagut, Xavier; Lymperidou, Aikaterini; Mateo-Navarro, Ramon; De Cid, Rafael; González Ruiz, Juan Ramon; Labarga, Alberto (2024). dsOMOP: Federated Analysis of Harmonized Clinical Data Combining OMOP CDM and DataSHIELD in a DATOS-CAT Cohort Use Case
Under Submission

SZTANDERA, K.; RODRIGUEZ GARCÍA, J.L. and CEÑA, V. In Vivo Applications of Dendrimers: A Step toward the Future of Nanoparticle-Mediated Therapeutics. Pharmaceutics 16:439. 2024.
DOI: 10.3390/pharmaceutics16040439.
URL: https://pubmed.ncbi.nlm.nih.gov/38675101/

2023

Daniel Sandín García , Javier Valle , Jordi Gómez , Laura Comas , Maria Nieves Larrosa , Juan José González , María Ángeles Jiménez , Daniel Sandín García , Javier Valle , Jordi Gómez , Laura Comas , Maria Nieves Larrosa , Juan José González , María Ángeles Jiménez , David Andreu and Marc Torrent (2023), Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria. bioRxiv, 2023.10.19.563059
DOI: 10.1101/2023.10.19.563059.
URL: https://www.biorxiv.org/content/10.1101/2023.10.19.563059v1

Durán-Rey, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; Sánchez-Margallo, JA; Crisóstomo, V; Irastorza, I; Silván, U; Lanceros-Méndez, S; Sánchez-Margallo, FM. Development of Silk Fibroin Scaffolds for Vascular Repair. Biomacromolecules. 2023 (IF: 6.979; Q1).
DOI: https://doi.org/10.3390/biom13091389
URL: https://www.mdpi.com/2480072

Gallart-Palau X, Lorca C, Mulet M, Sánchez Milán JA, Lisa J, Ngan SC, Iyappan R, Katoueezadeh M, Serra A, Sze SK. Differential systemic decellularization in vivo to study molecular changes in each vasculature layer in murine models of disease. STAR Protoc. 2023 Aug 24;4(3):102524
DOI: 10.1016/j.xpro.2023.102524.
URL: https://www.sciencedirect.com/science/article/pii/S2666166723004914

Gallego-Yerga, L.; Ceña, V. and Peláez, R. Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Evaluation as Novel Anticancer Agents. Pharmaceutics 15: 1698
DOI: 10.3390/pharmaceutics15061698
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/37376146/

Gil-Redondo R., Conde R., Bruzzone C., Seco ML, Bizkarguenaga, M, González-Valle B, de Diego A., Laín A., Habisch H., Haudum C., Verheyen N., Obermayer-Pietsch B., Margarita S., Pelusi S., Verde I., Oliveira N., Sousa A., Zabala-Letona A., Santos-Martin A., Loizaga-Iriarte A., Unda-Urzaiz M., Kazenwadel J., Berezhnoy G., Geisler T., Gawaz M., Cannet C., Schäfer H., Diercks T., Trautwein C., Carracedo A., Madl T., Valenti L., Spraul M., C Lu S. Embade N., Mato J.M., Millet O., The Lancet (Preprint), MetSCORE: a molecular metric to evaluate the risk of metabolic syndrome based on serum NMR metabolomics.
URL: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4625798

Gómez, Jordi and Torrent, Marc,  Structural assembly of the bacterial essential interactome. bioRxiv, 2023.06.14.544900
DOI: 10.1101/2023.06.14.544900
URL: https://www.biorxiv.org/content/10.1101/2023.06.14.544900v1.full

Grau, S; Vela, JM; Gurt, A; Barceló-Vidal, J; Ojeda, F; López, I; Gómez-García, L; Loza, MI; Martín-García, E; Maldonado, R; Monfort, J. Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients. Journal of Infection.
DOI: 10.1016/j.jinf.2023.11.008
URL: https://www.journalofinfection.com/article/S0163-4453(23)00562-5/fulltext

Liu, Xi; Jimenez-Alesanco, Ana; Zexian, Li; Neira, Jose Luis; Peng, Ling; Rizzuti, Bruno; Chuluyan, Eduardo; Velazquez-Campoy, Adrian; Xia, Yi; Abian, Olga; Santofimia-Castaño, Patricia; Iovanna, Juan. (2023) Development of an Efficient and Safe NUPR1 Inhibitor with Anticancer Activity.

LORENZO-LOZANO, M.C.; BLÁZQUEZ-MANZANERA, A.L. and CARNICERO, J.A. How kidney clock works: circadian pattern of eGFR based on a population data group. J Physiol Biochem 79: 543-554 .2023.
DOI: 10.1007/s13105-023-00948-2.

Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Kalani, Ladan; Jorge-Torres, Olga C.; Esteller, Manel; Ausio, Juan; Abian, Olga; Velazquez-Campoy, Adrian (2023) Extending MeCP2 interactome: Canonical nucleosomal histones interact with MeCP2. Nucleic Acids Research.
DOI: 10.1093/nar/gkae051
URL: https://academic.oup.com/nar/article/52/7/3636/7600452

RAKSHIT, S.; MALDONADO, A.; LEZAMA, L.; COHEN, B. and DOUHAL, A. The Effects of Mono – and Bivalent Linear Alkyl Interlayer Spacers on the Photobehavior of Mn (II)-Based Perovskites. Int. J. Mol. Sci. 24: 3280. 2023.
DOI: 10.3390/ijms24043280.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9967457/

Roy R, Lorca C, Mulet M, Sánchez Milán JA, Baratas A, de la Casa M, Espinet C, Serra A, Gallart-Palau X. Altered ureido protein modification profiles in seminal plasma extracellular vesicles of non-normozoospermic men. Front Endocrinol. 2023 Mar 22;14:1113824
DOI: 10.3389/fendo.2023.1113824.DOI
URL: https://www.frontiersin.org/articles/10.3389/fendo.2023.1113824/full

Sánchez Milán JA, Fernández-Rhodes M, Guo X, Mulet M, Ngan SC, Iyappan R, Katoueezadeh M, Sze SK, Serra A, Gallart-Palau X. Trioxidized cysteine in the aging proteome mimics the structural dynamics and interactome of phosphorylated serine. Aging Cell. 2023 Dec 18:e14062. doi: 10.1111/acel.14062.
URL: acel.14062

Sandín García D., , Valle Javier, Gómez Jordi, Comas Laura, Larrosa Maria Nieves, González Juan José, Jiménez María Ángeles, Andreu David and Torrent Marc (2023), Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria. bioRxiv, 2023.10.19.563059
DOI: 10.1101/2023.10.19.563059.
URL: https://www.biorxiv.org/content/10.1101/2023.10.19.563059v1

2022

 

De la Torre, C; Játiva, P; Posadas, I; Manzaranres, D; Jiménez, J.L; Ortiz, C; Fernández, J.M, y Ceña, V., A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells. Pharmaceutics 14: 2424. 2022.
DOI: 10.3390/pharmaceutics14112424.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/36365241/

Durán-Rey, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; Sánchez-Margallo, JA; Crisóstomo, V; Irastorza, I; Silván, U; Lanceros-Méndez, S; Sánchez-Margallo, FM. Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture. Frontiers in Bioengineering and Biotechnology. 2022 (IF: 6.064; Q1).
DOI: https://doi.org/10.3389/fbioe.2022.1044667
URL: https://www.frontiersin.org/articles/10.3389/fbioe.2022.1044667/full

PEREZ-CARRIÓN, M.D.; POSADAS, I.; SOLERA, J. and CEÑA, V. LRRK2 and Proteostasis in Parkinson’s Disease. Int. J. Mol. Sci. 23: 6808. 2022.
DOI: 10.3390/ijms23126808.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35743250/

POSADAS, I.; ROMERO-CASTILLO, L.; RONCA, R.A.; KARPUS, A.; MIGNANI, S.; MAJORAL, J.P.; MUÑOZ-FERNÁNDEZ, M.A. and CEÑA, V. Engineered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death. Int.J. Mol. Sci. 23: 4391. 2022.
DOI: 10.3390/ijms23084391.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024777/

SAROWAR, S.; CIRILLO, D.; JÁTIVA, P.; NILSEN, M.H.; OTRAGANE, S.A.; HEGGDAL, J.; SELHEIM, F.; CEÑA, V.; BJØRSVIK, H.R. and ENGER, P. Ø. The Styryl Benzoic Acid Derivative DC10 Potentiates Radiotherapy by Targeting the xCT-Glutathione Axis. Front. Oncol. 12: 786739. 2022.
DOI: 10.3389/fonc.2022.786739.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8858948/