TESIS DOCTORALS

“Hepatoencefalopatia deguda a mutacions a GFM1: obtenció d’un model de ratolí modificat genèticament i estudi preclínic de teràpia gènica amb vectors adenoassociats” , Programa de Doctorat en Bioquímica, Biologia Molecular i Biomedicina de la Universitat Autònoma de Barcelona.
(Projecte Col·laboratiu Catalunya: DRUG4-COXPD1)

“MNK inhibition as therapeutic approach for tumor sensitization to approved therapies” (en curs)
(Projecte Col·laboratiu Catalunya: MnkImmunOnco)

“Search for new therapeutic options in pediatric osteosarcoma using patient derived tumor cell lines”. Tesi doctoral iniciada l’1 de Setembre de 2023 que inclou la caracterització de compostos preseleccionats als screenings.
(Projecte Col·laboratiu Catalunya: OsteoMetTherapy)

“Use of siRNA a new therapy for glioblastoma”

“Advanced therapies for prostate cancer”

“In-Depth Characterization of Extracellular Vesicles for Their Use as Disease Biomarkers and Next-Generation Nanovectors”
(Projecte Col·laboratiu Catalunya: EVBRAINTARGET)

“Targeting the MNK/eIF4E axis in the tumor environment”
(Projecte Col·laboratiu Catalunya: MnkImmunOnco)

Anàlisi i validació de materials destinats al disseny d’empelts vasculars d’enginyeria tissular”

Tesi doctoral sobre estudi estructural i funcional de MeCP2 i avaluació de compostos que modulen la seva funció

Tesi doctoral sobre estudi estructural i funcional de BFT-3 i avaluació de compostos que modulen la seva funció

2023

Daniel Sandín García, Javier Valle, Jordi Gómez, Laura Comas, Maria Nieves Larrosa, Juan José González, Maria Àngels Jiménez, Daniel Sandín García, Javier Valle, Jordi Gómez, Laura Comas, Maria Nieves Larrosa, Juan José González, María Ángeles Jiménez, David Andreu i Marc Torrent (2023), mining l’heparinome per cryptic antimicrobial peptides que semblen kill gram-negatiu bacteri . bioRxiv, 2023.10.19.563059
DOI: 10.1101/2023.10.19.563059.
URL: https://www.biorxiv.org/content/10.1101/2023.10.19.563059v1

Durán-Rei, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; Sánchez-Margallo, JA; Crisòstom, V; Irastorza, I; Silvà, U; Lanceros-Méndez, S; Sánchez-Margallo, FM. Development of Silk Fibroin Scaffolds per Vascular Repair. Biomacromolecules. 2023 (IF: 6.979; Q1).
DOI: https://doi.org/10.3390/biom13091389
URL: https://www.mdpi.com/2480072

Gallart-Palau X, Lorca C, Mulet M, Sánchez Milà JA, Lisa J, Ngan SC, Iyappan R, Katoueezadeh M, Serra A, Sze SK. Differential systemic decel·lularization in vivo to study molecular changes in each vasculature layer in murine models of disease. STAR Protoc. 2023 Aug 24;4(3):102524
DOI: 10.1016/j.xpro.2023.102524.
URL: https://www.sciencedirect.com/science/article/pii/S2666166723004914

Gallec-Yerga, L.; Cenya, V. and Peláez, R. Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Avaluation as Novel Anticancer Agents. Pharmaceutics 15: 1698
DOI: 10.3390/pharmaceutics15061698
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/37376146/

Gil-Redondo R., Comte R., Bruzzone C., Sec ML, Bizkarguenaga, M, González-Vall B, de Diego A., Laín A., Habisch H., Haudum C., Verheyen N., Obermayer-Pietsch B., Margarita S., Pelusi S., Verd I., Oliveira N., Sousa A., Zabala-Letona A., Sants-Martin A., Loizaga-Iriarte A., Unda-Urzaiz M., Kazenwadel J. , Berezhnoy G., Geisler T., Gawaz M., Cannet C., Schäfer H., Diercks T., Trautwein C., Carracedo A., Madl T., Valenti L., Spraul M., C Lu S. Embade N., Mato JM, Millet O., The Lancet (Preprint), MetSCORE: a molecular mètric per avaluar el risc de metabòlic syndrome basat en serum NMR metabolòmics.
URL: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4625798

Gómez, Jordi i Torrent, Marc, Structural assembly of the bacterial essential interactome. bioRxiv, 2023.06.14.544900
DOI: 10.1101/2023.06.14.544900
URL: https://www.biorxiv.org/content/10.1101/2023.06.14.544900v1.full

Grau, S; Vela, JM; Gurt, A; Barceló-Vidal, J; Ojeda, F; López, I; Gómez-García, L; Loza, LA MEVA; Martín-García, I; Maldonado, R; Monfort, J. Efficacy de SIGMAR1-basat teràpia en el darrer tractament amb confirmat mild symptomatic COVID-19 patients. Journal of Infection.
DOI: 10.1016/j.jinf.2023.11.008
URL: https://www.journalofinfection.com/article/S0163-4453(23)00562-5/fulltext

Liu, Xi; Jimenez-Alesanco, Ana; Zexian, Li; Neira, Jose Luis; Peng, Ling; Rizzuti, Bruno; Chuluyan, Eduardo; Velazquez-Campoy, Adrian; Xia, Yi; Abian, Olga; Santofimia-Castaño, Patricia; Iovanna, Joan. (2023) Development of an Efficient and Safe NUPR1 Inhibitor with Anticancer Activity.

LORENZO-LOZANO, MC; BLÁZQUEZ-MANZANERA, AL CARNICER, JA How kidney clock works: circadian pattern of eGFR basat en population data group . J Physiol Biochem 79: 543-554 .2023.
DOI: 10.1007/s13105-023-00948-2.

Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Kalani, Ladan; Jorge-Torres, Olga C.; Esteller, Manel; Ausio, Juan; Abian, Olga; Velazquez-Campoy, Adrian (2023) Extending MeCP2 interactome: Canonical nucleosomal histons interact with MeCP2. Nucleic Acids Research.
DOI: 10.1093/nar/gkae051
URL: https://academic.oup.com/nar/article/52/7/3636/7600452

RAKSHIT, S.; MALDONAT, A.; LEZAMA, L.; COHEN, B. and DOUHAL, A. The Effects of Mono – and Bivalent Linear Alkyl Interlayer Spacers on el Photobehavior of Mn (II)-Based Perovskites . Int. J. Mol. Sci. 24: 3280. 2023.
DOI: 10.3390/ijms24043280.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9967457/

Roy R, Lorca C, Mulet M , Sánchez Milà JA, Barates A, de la Casa M, Espinet C, Serra A, Gallart-Palau X. Front Endocrinol. 2023 Mar 22;14:1113824
DOI: 10.3389/fend.2023.1113824.DOI
URL: https://www.frontiersin.org/articles/10.3389/fendo.2023.1113824/full

Sánchez Milà JA, Fernández-Rhodes M, Guo X, Mulet M, Ngan SC, Iyappan R, Katoueezadeh M, Sze SK, Serra A, Gallart-Palau X. Trioxidized cysteine ​​in aaging proteome mimics structural dynamics and interactome of phosphorylated serine. Aging Cell. 2023 Dec 18:e14062. doi: 10.1111/accel.14062.
URL: accel.14062

Sandín García D., , Valle Javier, Gómez Jordi, Comas Laura, Larrosa Maria Nieves, González Juan José, Jiménez Maria Àngels, Andreu David and Torrent Marc (2023), Mining l’heparinome per críptic antimicrobial peptides que selectively kill gram-negatiu bacteri . bioRxiv, 2023.10.19.563059
DOI: 10.1101/2023.10.19.563059.
URL: https://www.biorxiv.org/content/10.1101/2023.10.19.563059v1

2022

De la Torre, C; Xàtiva, P; Posades, I; Manzaranres, D; Jiménez, JL; Ortiz, C; Fernández, JM, i Ceña, V., A β-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells. Pharmaceutics 14: 2424. 2022.
DOI: 10.3390/pharmaceutics14112424.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/36365241/

Durán-Rei, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; Sánchez-Margallo, JA; Crisòstom, V; Irastorza, I; Silvà, U; Lanceros-Méndez, S; Sánchez-Margallo, FM. Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture . Frontiers in Bioengineering and Biotechnology. 2022 (IF: 6.064; Q1).
DOI: https://doi.org/10.3389/fbioe.2022.1044667
URL: https://www.frontiersin.org/articles/10.3389/fbioe.2022.1044667/full

PEREZ-CARRIÓN, MD; POSADES, I.; SOLERA, J. and CENYA, V. LRRK2 and Proteostasis in Parkinson’s Disease. Int. J. Mol. Sci. 23: 6808. 2022.
DOI: 10.3390/ijms23126808.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35743250/

POSADES, I.; ROMANÍ-CASTELL, L.; RONCA, RA; KARPUS, A.; MIGNANI, S.; MAJORAL, JP; MUÑOZ-FERNÁNDEZ, MA and CENYA, V. Enginered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death. Int.J. Mol. Sci. 23: 4391. 2022.
DOI: 10.3390/ijms23084391.
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024777/

SAROWAR, S.; CIRILLO, D.; JÀTIVA, P.; NILSEN, MH; OTRAGANE, SA; HEGGDAL, J.; SELHEIM, F.; CENERA, V.; BJØRSVIK, HR and ENGER, P. Ø. The Styryl Benzoic Acid Derivative DC10 Potentiates Radiotherapy by Targeting the xCT-Glutathione Axis . Front. Oncol. 12: 786739. 2022.
DOI: 10.3389/fonc.2022.786739.
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8858948/