{"id":17581,"date":"2024-11-05T16:05:56","date_gmt":"2024-11-05T16:05:56","guid":{"rendered":"https:\/\/planescomplementariossalud.es\/tesis-doctorales\/"},"modified":"2024-11-05T16:20:46","modified_gmt":"2024-11-05T16:20:46","slug":"tesis-doctorales","status":"publish","type":"page","link":"https:\/\/planescomplementariossalud.es\/eu\/tesis-doctorales\/","title":{"rendered":"Tesis doctorales"},"content":{"rendered":"\t\t
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DOKTORTZA-TESIAK

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\u201cHepatoencefalopat\u00eda debida a mutaciones en GFM1: obtenci\u00f3n de un modelo de rat\u00f3n modificado gen\u00e9ticamente y estudio precl\u00ednico de terapia g\u00e9nica con vectores adenoasociados\u201d<\/strong>, Programa de Doctorado en Bioqu\u00edmica, Biolog\u00eda Molecular y Biomedicina de la Universitat Aut\u00f2noma de Barcelona.
(Proyecto Colaborativo Catalu\u00f1a: DRUG4-COXPD1)<\/p>\n

“MNK inhibition as a therapeutic approach for tumor sensitization to approved therapies”<\/strong> (en curso)
(Proyecto Colaborativo Catalu\u00f1a: MnkImmunOnco)<\/p>\n

\u201cSearch for new therapeutic options in pediatric osteosarcoma using patient derived tumor cell lines\u201d.<\/strong> Tesis doctoral iniciada el 1 de Septiembre de 2023 que incluye la caracterizaci\u00f3n de compuestos pre-seleccionados en los screenings.
(Proyecto Colaborativo Catalu\u00f1a: OsteoMetTherapy)<\/p>\n

\u201cUse of siRNA as a new therapy for glioblastoma\u201d<\/strong><\/p>\n

\u201cAdvanced therapies for prostate cancer\u201d<\/strong><\/p>\n

\u201cIn-Depth Characterization of Extracellular Vesicles for Their Use as Disease Biomarkers and Next-Generation Nanovectors\u201d<\/strong>
(Proyecto Colaborativo Catalu\u00f1a: EVBRAINTARGET)<\/p>\n

\u201cTargeting the MNK\/eIF4E axis in the tumor environment\u201d<\/strong>
(Proyecto Colaborativo Catalu\u00f1a: MnkImmunOnco)<\/p>\n

\u201cAn\u00e1lisis y validaci\u00f3n de materiales destinados al dise\u00f1o de injertos vasculares de ingenier\u00eda tisular\u201d<\/strong><\/p>\n

Tesis doctoral sobre estudio estructural y funcional de MeCP2 y evaluaci\u00f3n de compuestos que modulan su funci\u00f3n<\/p>\n

Tesis doctoral sobre estudio estructural y funcional de BFT-3 y evaluaci\u00f3n de compuestos que modulan su funci\u00f3n<\/p><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2023<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Daniel Sand\u00edn Garc\u00eda , Javier Valle , Jordi G\u00f3mez , Laura Comas , Maria Nieves Larrosa , Juan Jos\u00e9 Gonz\u00e1lez , Mar\u00eda \u00c1ngeles Jim\u00e9nez , Daniel Sand\u00edn Garc\u00eda , Javier Valle , Jordi G\u00f3mez , Laura Comas , Maria Nieves Larrosa , Juan Jos\u00e9 Gonz\u00e1lez , Mar\u00eda \u00c1ngeles Jim\u00e9nez , David Andreu and Marc Torrent (2023), Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria<\/strong>. bioRxiv, 2023.10.19.563059
DOI: 10.1101\/2023.10.19.563059.
URL: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.19.563059v1<\/a> <\/p>\n

Dur\u00e1n-Rey, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; S\u00e1nchez-Margallo, JA; Cris\u00f3stomo, V; Irastorza, I; Silv\u00e1n, U; Lanceros-M\u00e9ndez, S; S\u00e1nchez-Margallo, FM. Development of Silk Fibroin Scaffolds for Vascular Repair. Biomacromolecules. <\/strong> 2023 (IF: 6.979; Q1).
DOI: https:\/\/doi.org\/10.3390\/biom13091389
URL: https:\/\/www.mdpi.com\/2480072<\/a><\/p>\n

Gallart-Palau X, Lorca C, Mulet M, S\u00e1nchez Mil\u00e1n JA, Lisa J, Ngan SC, Iyappan R, Katoueezadeh M, Serra A, Sze SK. Differential systemic decellularization in vivo to study molecular changes in each vasculature layer in murine models of disease.<\/strong> STAR Protoc. 2023 Aug 24;4(3):102524
DOI: 10.1016\/j.xpro.2023.102524.
URL: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666166723004914<\/a> <\/p>\n

Gallego-Yerga, L.; Ce\u00f1a, V. and Pel\u00e1ez, R. Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Evaluation as Novel Anticancer Agents.<\/strong> Pharmaceutics 15: 1698
DOI: 10.3390\/pharmaceutics15061698
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/37376146\/<\/a><\/span><\/p>\n

Gil-Redondo R., Conde R., Bruzzone C., Seco ML, Bizkarguenaga, M, Gonz\u00e1lez-Valle B, de Diego A., La\u00edn A., Habisch H., Haudum C., Verheyen N., Obermayer-Pietsch B., Margarita S., Pelusi S., Verde I., Oliveira N., Sousa A., Zabala-Letona A., Santos-Martin A., Loizaga-Iriarte A., Unda-Urzaiz M., Kazenwadel J., Berezhnoy G., Geisler T., Gawaz M., Cannet C., Sch\u00e4fer H., Diercks T., Trautwein C., Carracedo A., Madl T., Valenti L., Spraul M., C Lu S. Embade N., Mato J.M., Millet O., The Lancet (Preprint), MetSCORE: a molecular metric to evaluate the risk of metabolic syndrome based on serum NMR metabolomics.<\/strong>
URL: https:\/\/papers.ssrn.com\/sol3\/papers.cfm?abstract_id=4625798 <\/p>\n

G\u00f3mez, Jordi eta Torrent, Marc, Bakterioen interaktoma esentzialaren egitura-muntaia.<\/strong> bioRxiv, 2023.06.14.544900
DOI: 10.1101\/2023.06.14.544900
URLa: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.06.14.544900v1.full<\/a><\/p>\n

Grau, S; Vela, JM; Gurt, A; Barcel\u00f3-Vidal, J; Ojeda, F; L\u00f3pez, I; G\u00f3mez-Garc\u00eda, L; Loza, MI; Mart\u00edn-Garc\u00eda, E; Maldonado, R; Monfort, J. Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients.<\/strong> Journal of Infection.
DOI: 10.1016\/j.jinf.2023.11.008
URL: https:\/\/www.journalofinfection.com\/article\/S0163-4453(23)00562-5\/fulltext<\/a><\/p>\n

Liu, Xi; Jimenez-Alesanco, Ana; Zexian, Li; Neira, Jose Luis; Peng, Ling; Rizzuti, Bruno; Chuluyan, Eduardo; Velazquez-Campoy, Adrian; Xia, Yi; Abian, Olga; Santofimia-Casta\u00f1o, Patricia; Iovanna, Juan. (2023) Development of an Efficient and Safe NUPR1 Inhibitor with Anticancer Activity.
<\/strong><\/p>\n

LORENZO-LOZANO, M.C.; BL\u00c1ZQUEZ-MANZANERA, A.L. and CARNICERO, J.A. How kidney clock works: circadian pattern of eGFR based on a population data group<\/strong>. J Physiol Biochem 79: 543-554 .2023.
DOI: 10.1007\/s13105-023-00948-2.<\/p>\n

Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Kalani, Ladan; Jorge-Torres, Olga C.; Esteller, Manel; Ausio, Juan; Abian, Olga; Velazquez-Campoy, Adrian (2023) Extending MeCP2 interactome: Canonical nucleosomal histones interact with MeCP2.<\/strong> Nucleic Acids Research.
DOI: 10.1093\/nar\/gkae051
URL: https:\/\/academic.oup.com\/nar\/article\/52\/7\/3636\/7600452<\/a><\/p>\n

RAKSHIT, S.; MALDONADO, A.; LEZAMA, L.; COHEN, B. and DOUHAL, A. The Effects of Mono \u2013 and Bivalent Linear Alkyl Interlayer Spacers on the Photobehavior of Mn (II)-Based Perovskites<\/strong>. Int. J. Mol. Sci. 24: 3280. 2023.
DOI: 10.3390\/ijms24043280.
URL: http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc9967457\/<\/a> <\/p>\n

Roy R, Lorca C, Mulet M, S\u00e1nchez Mil\u00e1n JA, Baratas A, de la Casa M, Espinet C, Serra A, Gallart-Palau X. Altered ureido protein modification profiles in seminal plasma extracellular vesicles of non-normozoospermic men.<\/strong> Front Endocrinol. 2023 Mar 22;14:1113824
DOI: 10.3389\/fendo.2023.1113824.DOI
URL: https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2023.1113824\/full<\/a> <\/p>\n

S\u00e1nchez Mil\u00e1n JA, Fern\u00e1ndez-Rhodes M, Guo X, Mulet M, Ngan SC, Iyappan R, Katoueezadeh M, Sze SK, Serra A, Gallart-Palau X. Trioxidized cysteine in the aging proteome mimics the structural dynamics and interactome of phosphorylated serine. Aging Cell. <\/strong> 2023 Dec 18:e14062. doi: 10.1111\/acel.14062.
URL: acel.14062 <\/p>\n

Sand\u00edn Garc\u00eda D., , Valle Javier, G\u00f3mez Jordi, Comas Laura, Larrosa Maria Nieves, Gonz\u00e1lez Juan Jos\u00e9, Jim\u00e9nez Mar\u00eda \u00c1ngeles, Andreu David and Torrent Marc (2023), Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria<\/strong>. bioRxiv, 2023.10.19.563059
DOI: 10.1101\/2023.10.19.563059.
URL: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.19.563059v1 <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2022<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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De la Torre, C; J\u00e1tiva, P; Posadas, I; Manzaranres, D; Jim\u00e9nez, J.L; Ortiz, C; Fern\u00e1ndez, J.M, y Ce\u00f1a, V., A \u03b2-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells.<\/strong> Pharmaceutics 14: 2424. 2022.
DOI: 10.3390\/pharmaceutics14112424.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/36365241\/<\/a> <\/p>\n

Dur\u00e1n-Rey, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; S\u00e1nchez-Margallo, JA; Cris\u00f3stomo, V; Irastorza, I; Silv\u00e1n, U; Lanceros-M\u00e9ndez, S; S\u00e1nchez-Margallo, FM. Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture<\/strong>. Frontiers in Bioengineering and Biotechnology. 2022 (IF: 6.064; Q1).
DOI: https:\/\/doi.org\/10.3389\/fbioe.2022.1044667
URL: https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2022.1044667\/full<\/a> <\/p>\n

PEREZ-CARRI\u00d3N, M.D.; POSADAS, I.; SOLERA, J. and CE\u00d1A, V. LRRK2 and Proteostasis in Parkinson’s Disease.<\/strong> Int. J. Mol. Sci. 23: 6808. 2022.
DOI: 10.3390\/ijms23126808.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/35743250\/<\/a> <\/p>\n

POSADAS, I.; ROMERO-CASTILLO, L.; RONCA, R.A.; KARPUS, A.; MIGNANI, S.; MAJORAL, J.P.; MU\u00d1OZ-FERN\u00c1NDEZ, M.A. and CE\u00d1A, V. Engineered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death.<\/strong> Int.J. Mol. Sci. 23: 4391. 2022.
DOI: 10.3390\/ijms23084391.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9024777\/<\/a> <\/p>\n

SAROWAR, S.; CIRILLO, D.; J\u00c1TIVA, P.; NILSEN, M.H.; OTRAGANE, S.A.; HEGGDAL, J.; SELHEIM, F.; CE\u00d1A, V.; BJ\u00d8RSVIK, H.R. and ENGER, P. \u00d8. The Styryl Benzoic Acid Derivative DC10 Potentiates Radiotherapy by Targeting the xCT-Glutathione Axis <\/strong>. Front. Oncol. 12: 786739. 2022.
DOI: 10.3389\/fonc.2022.786739.
URL: http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc8858948\/<\/a> <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

DOKTORTZA-TESIAK \u201cHepatoencefalopat\u00eda debida a mutaciones en GFM1: obtenci\u00f3n de un modelo de rat\u00f3n modificado gen\u00e9ticamente y estudio precl\u00ednico de terapia g\u00e9nica con vectores adenoasociados\u201d, Programa de Doctorado en Bioqu\u00edmica, Biolog\u00eda Molecular y Biomedicina de la Universitat Aut\u00f2noma de Barcelona.(Proyecto Colaborativo Catalu\u00f1a: DRUG4-COXPD1) “MNK inhibition as a therapeutic approach for tumor sensitization to approved therapies” (en …<\/p>\n

Tesis doctorales<\/span> Read More »<\/a><\/p>\n","protected":false},"author":15,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-17581","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/pages\/17581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/comments?post=17581"}],"version-history":[{"count":4,"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/pages\/17581\/revisions"}],"predecessor-version":[{"id":17586,"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/pages\/17581\/revisions\/17586"}],"wp:attachment":[{"href":"https:\/\/planescomplementariossalud.es\/eu\/wp-json\/wp\/v2\/media?parent=17581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}