{"id":17574,"date":"2024-11-05T16:05:56","date_gmt":"2024-11-05T16:05:56","guid":{"rendered":"https:\/\/planescomplementariossalud.es\/tesis-doctorals\/"},"modified":"2024-11-05T16:21:19","modified_gmt":"2024-11-05T16:21:19","slug":"tesis-doctorals","status":"publish","type":"page","link":"https:\/\/planescomplementariossalud.es\/ca\/tesis-doctorals\/","title":{"rendered":"Tesis doctorals"},"content":{"rendered":"\t\t
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TESIS DOCTORALS

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“Hepatoencefalopatia deguda a mutacions a GFM1: obtenci\u00f3 d’un model de ratol\u00ed modificat gen\u00e8ticament i estudi precl\u00ednic de ter\u00e0pia g\u00e8nica amb vectors adenoassociats”<\/strong> , Programa de Doctorat en Bioqu\u00edmica, Biologia Molecular i Biomedicina de la Universitat Aut\u00f2noma de Barcelona.
(Projecte Col\u00b7laboratiu Catalunya: DRUG4-COXPD1)<\/p>\n

“MNK inhibition as therapeutic approach for tumor sensitization to approved therapies”<\/strong> (en curs)
(Projecte Col\u00b7laboratiu Catalunya: MnkImmunOnco)<\/p>\n

\u201cSearch for new therapeutic options in pediatric osteosarcoma using patient derived tumor cell lines\u201d.<\/strong> Tesi doctoral iniciada l’1 de Setembre de 2023 que inclou la caracteritzaci\u00f3 de compostos preseleccionats als screenings.
(Projecte Col\u00b7laboratiu Catalunya: OsteoMetTherapy)<\/p>\n

\u201cUse of siRNA a new therapy for glioblastoma\u201d<\/strong><\/p>\n

\u201cAdvanced therapies for prostate cancer\u201d<\/strong><\/p>\n

\u201cIn-Depth Characterization of Extracellular Vesicles for Their Use as Disease Biomarkers and Next-Generation Nanovectors\u201d<\/strong>
(Projecte Col\u00b7laboratiu Catalunya: EVBRAINTARGET)<\/p>\n

\u201cTargeting the MNK\/eIF4E axis in the tumor environment\u201d<\/strong>
(Projecte Col\u00b7laboratiu Catalunya: MnkImmunOnco)<\/p>\n

An\u00e0lisi i validaci\u00f3 de materials destinats al disseny d’empelts vasculars d’enginyeria tissular\u201d<\/strong><\/p>\n

Tesi doctoral sobre estudi estructural i funcional de MeCP2 i avaluaci\u00f3 de compostos que modulen la seva funci\u00f3<\/p>\n

Tesi doctoral sobre estudi estructural i funcional de BFT-3 i avaluaci\u00f3 de compostos que modulen la seva funci\u00f3<\/p><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2023<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Daniel Sand\u00edn Garc\u00eda, Javier Valle, Jordi G\u00f3mez, Laura Comas, Maria Nieves Larrosa, Juan Jos\u00e9 Gonz\u00e1lez, Maria \u00c0ngels Jim\u00e9nez, Daniel Sand\u00edn Garc\u00eda, Javier Valle, Jordi G\u00f3mez, Laura Comas, Maria Nieves Larrosa, Juan Jos\u00e9 Gonz\u00e1lez, Mar\u00eda \u00c1ngeles Jim\u00e9nez, David Andreu i Marc Torrent (2023), mining l’heparinome per cryptic antimicrobial peptides que semblen kill gram-negatiu bacteri<\/strong> . bioRxiv, 2023.10.19.563059
DOI: 10.1101\/2023.10.19.563059.
URL: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.19.563059v1<\/a> <\/p>\n

Dur\u00e1n-Rei, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; S\u00e1nchez-Margallo, JA; Cris\u00f2stom, V; Irastorza, I; Silv\u00e0, U; Lanceros-M\u00e9ndez, S; S\u00e1nchez-Margallo, FM. Development of Silk Fibroin Scaffolds per Vascular Repair. Biomacromolecules. <\/strong> 2023 (IF: 6.979; Q1).
DOI: https:\/\/doi.org\/10.3390\/biom13091389
URL: https:\/\/www.mdpi.com\/2480072<\/a><\/p>\n

Gallart-Palau X, Lorca C, Mulet M, S\u00e1nchez Mil\u00e0 JA, Lisa J, Ngan SC, Iyappan R, Katoueezadeh M, Serra A, Sze SK. Differential systemic decel\u00b7lularization in vivo to study molecular changes in each vasculature layer in murine models of disease.<\/strong> STAR Protoc. 2023 Aug 24;4(3):102524
DOI: 10.1016\/j.xpro.2023.102524.
URL: https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666166723004914<\/a> <\/p>\n

Gallec-Yerga, L.; Cenya, V. and Pel\u00e1ez, R. Potent and Selective Benzothiazole-Based Antimitotics with Improved Water Solubility: Design, Synthesis, and Avaluation as Novel Anticancer Agents.<\/strong> Pharmaceutics 15: 1698
DOI: 10.3390\/pharmaceutics15061698
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/37376146\/<\/a><\/span><\/p>\n

Gil-Redondo R., Comte R., Bruzzone C., Sec ML, Bizkarguenaga, M, Gonz\u00e1lez-Vall B, de Diego A., La\u00edn A., Habisch H., Haudum C., Verheyen N., Obermayer-Pietsch B., Margarita S., Pelusi S., Verd I., Oliveira N., Sousa A., Zabala-Letona A., Sants-Martin A., Loizaga-Iriarte A., Unda-Urzaiz M., Kazenwadel J. , Berezhnoy G., Geisler T., Gawaz M., Cannet C., Sch\u00e4fer H., Diercks T., Trautwein C., Carracedo A., Madl T., Valenti L., Spraul M., C Lu S. Embade N., Mato JM, Millet O., The Lancet (Preprint), MetSCORE: a molecular m\u00e8tric per avaluar el risc de metab\u00f2lic syndrome basat en serum NMR metabol\u00f2mics.<\/strong>
URL: https:\/\/papers.ssrn.com\/sol3\/papers.cfm?abstract_id=4625798 <\/p>\n

G\u00f3mez, Jordi i Torrent, Marc, Structural assembly of the bacterial essential interactome.<\/strong> bioRxiv, 2023.06.14.544900
DOI: 10.1101\/2023.06.14.544900
URL: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.06.14.544900v1.full<\/a><\/p>\n

Grau, S; Vela, JM; Gurt, A; Barcel\u00f3-Vidal, J; Ojeda, F; L\u00f3pez, I; G\u00f3mez-Garc\u00eda, L; Loza, LA MEVA; Mart\u00edn-Garc\u00eda, I; Maldonado, R; Monfort, J. Efficacy de SIGMAR1-basat ter\u00e0pia en el darrer tractament amb confirmat mild symptomatic COVID-19 patients.<\/strong> Journal of Infection.
DOI: 10.1016\/j.jinf.2023.11.008
URL: https:\/\/www.journalofinfection.com\/article\/S0163-4453(23)00562-5\/fulltext<\/a><\/p>\n

Liu, Xi; Jimenez-Alesanco, Ana; Zexian, Li; Neira, Jose Luis; Peng, Ling; Rizzuti, Bruno; Chuluyan, Eduardo; Velazquez-Campoy, Adrian; Xia, Yi; Abian, Olga; Santofimia-Casta\u00f1o, Patricia; Iovanna, Joan. (2023) Development of an Efficient and Safe NUPR1 Inhibitor with Anticancer Activity.
<\/strong><\/p>\n

LORENZO-LOZANO, MC; BL\u00c1ZQUEZ-MANZANERA, AL CARNICER, JA How kidney clock works: circadian pattern of eGFR basat en population data group<\/strong> . J Physiol Biochem 79: 543-554 .2023.
DOI: 10.1007\/s13105-023-00948-2.<\/p>\n

Ortega-Alarcon, David; Claveria-Gimeno, Rafael; Vega, Sonia; Kalani, Ladan; Jorge-Torres, Olga C.; Esteller, Manel; Ausio, Juan; Abian, Olga; Velazquez-Campoy, Adrian (2023) Extending MeCP2 interactome: Canonical nucleosomal histons interact with MeCP2.<\/strong> Nucleic Acids Research.
DOI: 10.1093\/nar\/gkae051
URL: https:\/\/academic.oup.com\/nar\/article\/52\/7\/3636\/7600452<\/a><\/p>\n

RAKSHIT, S.; MALDONAT, A.; LEZAMA, L.; COHEN, B. and DOUHAL, A. The Effects of Mono \u2013 and Bivalent Linear Alkyl Interlayer Spacers on el Photobehavior of Mn (II)-Based Perovskites<\/strong> . Int. J. Mol. Sci. 24: 3280. 2023.
DOI: 10.3390\/ijms24043280.
URL: http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc9967457\/<\/a> <\/p>\n

Roy R, Lorca C, Mulet M<\/strong> , S\u00e1nchez Mil\u00e0 JA, Barates A, de la Casa M, Espinet C, Serra A, Gallart-Palau X. Front Endocrinol. 2023 Mar 22;14:1113824
DOI: 10.3389\/fend.2023.1113824.DOI
URL: https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2023.1113824\/full<\/a> <\/p>\n

S\u00e1nchez Mil\u00e0 JA, Fern\u00e1ndez-Rhodes M, Guo X, Mulet M, Ngan SC, Iyappan R, Katoueezadeh M, Sze SK, Serra A, Gallart-Palau X. Trioxidized cysteine \u200b\u200bin aaging proteome mimics structural dynamics and interactome of phosphorylated serine. Aging Cell. <\/strong> 2023 Dec 18:e14062. doi: 10.1111\/accel.14062.
URL: accel.14062 <\/p>\n

Sand\u00edn Garc\u00eda D., , Valle Javier, G\u00f3mez Jordi, Comas Laura, Larrosa Maria Nieves, Gonz\u00e1lez Juan Jos\u00e9, Jim\u00e9nez Maria \u00c0ngels, Andreu David and Torrent Marc (2023), Mining l’heparinome per cr\u00edptic antimicrobial peptides que selectively kill gram-negatiu bacteri<\/strong> . bioRxiv, 2023.10.19.563059
DOI: 10.1101\/2023.10.19.563059.
URL: https:\/\/www.biorxiv.org\/content\/10.1101\/2023.10.19.563059v1 <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2022<\/b><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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De la Torre, C; X\u00e0tiva, P; Posades, I; Manzaranres, D; Jim\u00e9nez, JL; Ortiz, C; Fern\u00e1ndez, JM, i Ce\u00f1a, V., A \u03b2-Cyclodextrin-Based Nanoparticle with Very High Transfection Efficiency Unveils siRNA-Activated TLR3 Responses in Human Prostate Cancer Cells.<\/strong> Pharmaceutics 14: 2424. 2022.
DOI: 10.3390\/pharmaceutics14112424.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/36365241\/<\/a> <\/p>\n

Dur\u00e1n-Rei, D; Brito-Pereira, R; Ribeiro, C; Ribeiro, S; S\u00e1nchez-Margallo, JA; Cris\u00f2stom, V; Irastorza, I; Silv\u00e0, U; Lanceros-M\u00e9ndez, S; S\u00e1nchez-Margallo, FM. Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture<\/strong> . Frontiers in Bioengineering and Biotechnology. 2022 (IF: 6.064; Q1).
DOI: https:\/\/doi.org\/10.3389\/fbioe.2022.1044667
URL: https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2022.1044667\/full<\/a> <\/p>\n

PEREZ-CARRI\u00d3N, MD; POSADES, I.; SOLERA, J. and CENYA, V. LRRK2 and Proteostasis in Parkinson’s Disease.<\/strong> Int. J. Mol. Sci. 23: 6808. 2022.
DOI: 10.3390\/ijms23126808.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmid\/35743250\/<\/a> <\/p>\n

POSADES, I.; ROMAN\u00cd-CASTELL, L.; RONCA, RA; KARPUS, A.; MIGNANI, S.; MAJORAL, JP; MU\u00d1OZ-FERN\u00c1NDEZ, MA and CENYA, V. Enginered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death.<\/strong> Int.J. Mol. Sci. 23: 4391. 2022.
DOI: 10.3390\/ijms23084391.
URL: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9024777\/<\/a> <\/p>\n

SAROWAR, S.; CIRILLO, D.; J\u00c0TIVA, P.; NILSEN, MH; OTRAGANE, SA; HEGGDAL, J.; SELHEIM, F.; CENERA, V.; BJ\u00d8RSVIK, HR and ENGER, P. \u00d8. The Styryl Benzoic Acid Derivative DC10 Potentiates Radiotherapy by Targeting the xCT-Glutathione Axis <\/strong>. Front. Oncol. 12: 786739. 2022.
DOI: 10.3389\/fonc.2022.786739.
URL: http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc8858948\/<\/a> <\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

TESIS DOCTORALS “Hepatoencefalopatia deguda a mutacions a GFM1: obtenci\u00f3 d’un model de ratol\u00ed modificat gen\u00e8ticament i estudi precl\u00ednic de ter\u00e0pia g\u00e8nica amb vectors adenoassociats” , Programa de Doctorat en Bioqu\u00edmica, Biologia Molecular i Biomedicina de la Universitat Aut\u00f2noma de Barcelona. (Projecte Col\u00b7laboratiu Catalunya: DRUG4-COXPD1) “MNK inhibition as therapeutic approach for tumor sensitization to approved therapies” …<\/p>\n

Tesis doctorals<\/span> Llegeix m\u00e9s »<\/a><\/p>\n","protected":false},"author":15,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-17574","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/pages\/17574","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/comments?post=17574"}],"version-history":[{"count":4,"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/pages\/17574\/revisions"}],"predecessor-version":[{"id":17589,"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/pages\/17574\/revisions\/17589"}],"wp:attachment":[{"href":"https:\/\/planescomplementariossalud.es\/ca\/wp-json\/wp\/v2\/media?parent=17574"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}